{"id":4585,"date":"2020-05-08T09:47:26","date_gmt":"2020-05-08T13:47:26","guid":{"rendered":"https:\/\/motivationminceur.webloft.cloud\/neurocognitive-and-hormonal-correlates-of-voluntary-weight-loss-in-humans-2\/"},"modified":"2026-07-10T15:10:06","modified_gmt":"2026-07-10T19:10:06","slug":"neurocognitive-and-hormonal-correlates-of-voluntary-weight-loss-in-humans-2","status":"publish","type":"post","link":"https:\/\/motivationminceur.webloft.cloud\/en\/neurocognitive-and-hormonal-correlates-of-voluntary-weight-loss-in-humans-2\/","title":{"rendered":"Neurocognitive and Hormonal Correlates of Voluntary Weight Loss in Humans"},"content":{"rendered":"<div class=\"column\">\n<h1>Neurocognitive and Hormonal Correlates of Voluntary Weight Loss in Humans<\/h1>\n<p>Insufficient responses to hypocaloric diets have been attributed to hormonal adaptations that override self- control of food intake. We tested this hypothesis by measuring circulating energy-balance hormones and brain functional magnetic resonance imaging reactivity to food cues in 24 overweight\/obese participants before, and 1 and 3 months after starting a calorie restriction diet. Increased activity and functional connectivity in prefrontal regions at month 1 correlated with weight loss at months 1 and 3. Weight loss was also correlated with increased plasma ghrelin and decreased leptin, and these changes were associated with food cue reactivity in reward-related brain regions. However, the reduction in leptin did not counteract weight loss; indeed, it was correlated with further weight loss at month 3. Activation in prefrontal regions associated with self-control could contribute to successful weight loss and maintenance. This work supports the role of higher-level cognitive brain function in body-weight regulation in humans.<\/p>\n<\/div>\n<h2>Contacter nous pour plus de d\u00e9tails: <a href=\"mailto:info@motivationminceur.ca\">info@motivationminceur.ca<\/a><\/h2>\n","protected":false},"excerpt":{"rendered":"<p>Neurocognitive and Hormonal Correlates of Voluntary Weight Loss in Humans Insufficient responses to hypocaloric diets have been attributed to hormonal adaptations that override self- control of food intake. We tested this hypothesis by measuring circulating energy-balance hormones and brain functional magnetic resonance imaging reactivity to food cues in 24 overweight\/obese participants before, and 1 and [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-4585","post","type-post","status-publish","format-standard","hentry","category-blog"],"yoast_head":"<title>Neurocognitive and Hormonal Correlates of Voluntary Wei | Motivation Minceur<\/title>\n<meta name=\"description\" content=\"Expert weight loss: Neurocognitive and Hormonal Correlates of Voluntary Weight Loss in Humans. 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